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It is actually shown that 5F-MDMB-PICA is often a strong SCRA, and subtle alterations to go group composition can have profound affect on pharmacological results at CB1.Table 1 Affinities of your investigated indoles, indazoles and carbazoles with the cannabinoid CB1 and CB2 receptors identified in radioligand binding assaysIt functions as being a

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根据相关法律法规和本站规定,单位或个人购买相关危险物品应取得有效的资质、资格条件。Results of cannabinoid agonists and antagonists in male rats discriminating the synthetic cannabinoid AM2201.The case of David Mitchell Rozga, an American teen from Indianola, Iowa, introduced Worldwide notice to K2. Rozga shot

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-(five-hydroxypentyl) located in the existing research exhibit this metabolite is not likely to add to pharmacodynamic results of subcutaneously administered AM-2201. It truly is noteworthy that human consumers normally self-administer AM-2201 by smoking or vaping, but we have been unable to use both of such routes. The subcutaneous route was picke

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In a past examine [25], we had identified the pharmacological Homes of 48 synthetic cannabinoids gathered by the Institute of Forensic Drugs of the College of Bonn. In the existing analyze, we investigated the affinities and purposeful Houses of a fresh series of 42 synthetic cannabinoids, sixteen of which have not been noted as cannabinoid recepto

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Rat Mind cannabinoid receptor was stably transfected in to the murine tumor line AtT-20 to review its coupling to inwardly rectifying potassium currents and higher voltage-activated calcium currents and an endogenous cannabinoid, anandamide, activated Kir and inhibited ICa as efficaciously as powerful cannabinoid agonist.Nine human recombinant urid

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